Seminar – Erin W. Dickie

SEMINAR UNF SERIES Speaker: Dr Erin W. Dickie Title: Personalized Connectomics for the Study of Brain Health and Disease: Applications to Autism Spectrum Disorder and Schizophrenia Research. Where: CRIUGM Room E1910 (http://www.criugm.qc.ca/en/contact.html) When: Thursday May 24th,  13h-14h *The seminar will be presented in English Dr. Erin Dickie (PhD, Neurological Sciences, McGill University) is a Project Scientist. Dr. Dickie’s research focus is personalized connectomics, or the ability to map brain organization at the level of the individual. Individual mapping of brain function may be a critical first step in the design of targets for stimulation therapy. Dr. Dickie recently submitted a manuscript describing her tool for mapping neurodiversity (PINT), and showed that the brains of those affected by autism and more variable in their organization that those of typically developing controls. This work suggests that personalized brain mapping might be a critical first step for future biomarker discovery. Dr. Dickie also assists with the lab’s data management and analysis system, and builds automated tools for data analysis. In the past year, she has developed a new tool for surface-based analyses (ciftify) that has been publicly available and adopted by international groups. Abstract: Emerging work from the neuroimaging community shows that everyone’s cerebral cortex has a unique functionally organisation and that this unique organisation can be mapped using neuroimaging data at the individual participant level. To do so, we start with an analytic approach, using the CIFTI file format, that allows for a more neuroanatomically-faithful representation of data. An open source set of tools ‘ciftify’ (https://edickie.github.io/ciftify) make this approach more accessible to the greater scientific community. We than introduce novel methods...

Seminar – Tal Yarkoni

SEMINAR UNF SERIES Speaker: Dr Tal Yarkoni Title: How to survive and thrive as an open scientist Where: CRIUGM Amphithéâtre Le Groupe Maurice (http://www.criugm.qc.ca/en/contact.html) When: Thursday May 17th,  13h-14h *The seminar will be presented in English Dr Yarkoni is a Research Assistant Professor in the Department of Psychology at the University of Texas, where he directs the Psychoinformatics Lab. His research focuses on the development and application of new methods for acquiring, organizing, and synthesizing psychological data on a large scale. Tal’s work applies techniques from behavioral psychology, functional neuroimaging, and computer science to multiple domains within psychology, with a particular focus on personality and individual differences. Abstract: In principle, science is a cumulative, community-driven enterprise. To make new discoveries, researchers build directly on the products of other researchers’ efforts, and in turn, reciprocally share their own findings with the world. In practice, of course, things rarely proceed quite so idealistically. Researchers regularly hide their latest findings from one another as they compete for publication in rarified journals; data and protocols are hoarded to maintain competitive advantage; and “Questionable Research Practices” such as optional stopping and selective reporting are engaged in with alarming frequency, often under the justification that there is no other way for a modern scientist to succeed. In this talk I take issue with this philosophy, and argue that it is indeed possible for an open scientist to both survive and thrive in the modern environment. I review a series of open practices that can help advance one’s career while simultaneously maximizing the reproducibility, reliability, and accessibility of one’s scientific work. These include preprint deposition, open-access publication, preregistration, version...

Seminar – Daniel Margulies

SEMINAR UNF SERIES Speaker: Dr Daniel Margulies Title: Topographic principles of macroscale cortical connectivity Where: CRIUGM Amphithéâtre Le Groupe Maurice (http://www.criugm.qc.ca/en/contact.html) When: Wednesday May 16th,  13h-14h *The seminar will be presented in English Dr Margulies investigates the organization of large-scale brain networks, primarily through the analysis of intrinsic activity as measured with functional magnetic resonance imaging (fMRI). He has developed approaches to define sub regions within complex cortical areas, conducted cross-species comparative neuroanatomical studies, and related variation in these networks to phenotypic differences across individuals. His current research addresses the emergence of network topography and its relationship to cortical structure. Abstract: What determines the spatial arrangement of distinct areas of the cerebral cortex? Insights into functional processing streams indicate that areas are arranged stepwise, such that adjacent spatial position along the cortical mantle represents functional gradients. Having been largely restricted to describing processing within specific sensory modalities, how do these principles generalize across modalities and extend to the surrounding association cortex? I will present recent work describing various features of a principal gradient in cortical connectivity that spans between primary sensory/motor areas and higher-order transmodal association regions that in humans are known as the default-mode network. This arrangement suggests developmental mechanisms giving rise to the spatial distribution of cortical functions, and provides an anatomical scaffolding for investigating the propagation of information at both local and distributed spatial...

Seminar – Cyril Pernet

Présentateur/ Speaker:              Dr Cyril Pernet Titre/  Title:                                  On the simple relationships between brain and age: impact of methods and choices. Endroit/ Where:                          CRIUGM (http://www.criugm.qc.ca/en/contact.html), room E1910 Date/ When:                                 Vendredi 4 mai, 13h-14h/ Friday May 4th 1pm-2pm *La conférence sera présentée en anglais/The seminar will be present in English Dr Pernet obtained a PhD in Cognitive Neuropsychology from the University of Toulouse in France in 2004. He joined the Brain Research Imaging Center, Edinburgh in 2007, as fMRI lead for SINPASE (Scottish Imaging Network A Platform for Scientific Excellence). He is now an Academic Fellow, teaching fMRI/EEG and researching in the areas of visual and auditory categorization and language with a focus on methods (statistics) and clinical applications (brain tumors, stroke). He is also the Edinburg Imaging scientific contact for functional MRI studies, a lead advocate for open science and the organizer of many courses on brain imaging. Abstract: Using a simple all brain volume and VBM approach to ageing, I will present various methods and analysis choices that can greatly impact...

Brainhack Global 2018

The goal of the hackathon is to bring together researchers with disparate backgrounds to collaborate on open science projects in neuroimaging. Brainhack Montreal 2018 is part of the Brainhack Global 2018, with simultaneous hackathons running at more than 30 sites across the globe. Participants are encouraged to post project ideas on the website of brainhack Montreal. Dates: April 26th-27th, 2018 Costs: $30 CAD, includes onsite breakfast and lunch for two days Location: Centre de Recherche de l’Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada. Website: https://brainhack101.github.io/mtl-brainhack-2018 Brainhack Montreal is grateful for the support of the Québec BioImaging...

UNF seminars for 2018

  Speaker Title Room Time April 2018 April 25 Ella Gabitov Uncovering neural dynamics during continuous motor performance by modelling single events E-1910 13h00 May 2018 May 4 Cyril Pernet On the simple relationships between brain and age : impact of methods and choices E-1910 13h00 May 16 Daniel Margulies Topographic principles of macroscale cortical connectivity Amphithéâtre Le Groupe Maurice 13h00 May 17 Tal Yarkoni How to survive and thrive as an open scientist Amphithéâtre Le Groupe Maurice 13h00 May 24 Erin W. Dickie Personalized Connectomics for the Study of Brain Health and Disease: Applications to Autism Spectrum Disorder and Schizophrenia Research. E-1910 13h00 May 31 Anisha Keshavan Leveraging Web Technology to address challenges with Big Data in Neuroscience. E-1910 13h00 June 2018 June 7 Benjamin DeLeener The MRI anatomy of the spinal cord, Part I E-1910 13h00 August 2018 August 6 Anders Eklund Cluster failure revisited: Impact of first level design and physiological noise on cluster false positive rates. E-1910...

UNF special seminar

False Discovery Rate Control Under Rounding of P-Values Dr Hien Nguyen Location : CRIUGM (http://www.criugm.qc.ca/en/contact.html), room M6804 Date: December 13th, 13h-14h The seminar will be presented in English Dr Hien Nguyen is going to give special seminar of Unité de Neuroimagerie Fonctionnelle (UNF) this coming Wednesday. Dr Nguyen is a Lecturer and Australia Research Council DECRA Research Fellow at La Trobe University in Melbourne Australia. His research currently focuses on the development of Big Data methodologies that are deployable on small-scale computing infrastructures, and deep learning and neural networks for applications in personalised medicine. Summary: The mitigation of false positives is an important issue when conducting multiple hypothesis testing. The most popular paradigm for false positives mitigation is via the control of the false discovery rate (FDR). We present a method for FDR control that is applicable in cases where only p-values are available, and when those p-values are potentially equal to zero or one. Our method is based on an empirical-based paradigm where the Probit transformation of the p-values (called the z-scores) are modeled as a two-component mixture of normal distributions. Due to the rounding of the p-values, the usual approach for fitting mixture models cannot be applied. We instead use a binned data technique, which can be proved to consistently estimate the z-score distribution, even when the data are correlated. A simulation study shows that our methodology is competitive with popular alternatives, especially when data are correlated. We demonstrate the applicability of our methodology in practice via a brain imaging study of...

UNF 10th Anniversary

It is with great pleasure that we invite you to celebrate the 10th anniversary of the Functional neuroimaging unit (UNF). For this occasion, three internationally renowned researchers will share the latest knowledge in their respective fields. We will welcome you on Monday, September 22nd, 2014 at 1:00 p.m.at the Amphitheatre National Bank, Hautes Études Commerciales (HEC), 3000 Chemin de la Côte-Sainte-Catherine. A detailed program will follow shortly.   Adrian Owen, Ph.D. Brain and Mind Institute Department of Psychology University of Western Ontario, London, Ontario, Canada http://www.owenlab.uwo.ca/   “The search for consciousness: what has neuroimaging told us?” Randy McIntosh, Ph.D. Director, Rotman Research Institute Vice President Research, Baycrest Centre, Toronto, Canada http://www.baycrest.org/research/rotman-research-institute/labs-and-programs/mcintosh-lab/   “Does building a virtual brain to understand human cognition makes sense?”   Denis Le Bihan, M.D., Ph.D. Director, NeuroSpin, France http://www.meteoreservice.com/dlb.htm   “ What water tells us about the brain: The magic of diffusion MRI”...

Welcome to the UNF

The UNF (Unité de Neuroimagerie Fonctionnelle) of the Centre de recherche de l’Institut universitaire de gériatrie de Montréal (CRIUGM) is solely dedicated to research in neuroimaging. Researchers from Université de Montréal and affiliates (research centers and faculty members) from Canada and around the globe can benefit from its state-of-the-art...